allopurinol 300 - A New Gout Drug. Febuxostat wins marketing approval in the European Union
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A New Gout Drug. Febuxostat wins marketing approval in the European Union

It has taken a very long time for a major new gout drug to be developed and approved. Probably the best gout news in over 40 years, is that Febuxostat, which has been given the trade/brand name of Adenuric, has been approved by the European Medicines Agency for marketing in European Union (EU) countries.


It will also only be used in gout patients who have chronic hyperuricemia (high UA levels) and gout. So if you're a gout sufferer who lives in a European country that's a member of the EU, you can ask your doctor's opinion about whether Febuxostat is suitable for you.


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"week ago i couldnt walk and was in terible pain. i though my big toe was broken i would need a surgery, but doctor said it was gout. After taking some pain killer and goutezol for 2 days i can walk again. thank you" Peter from Chicago
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 It is 2:00 a.m. You sleep soundly after savoring a scrumptious surf and turf dinner at the best restaurant in town. Suddenly an intense stinging pain caused by the soft cotton sheet resting against your big toe awakens you with a jolt! This could be an acute attack of Gout, the aftermath of a high-protein diet.

A European study reported a 16 year follow-up of over 9,000 men between 41 and 63 who entered the study with no evidence of coronary heart disease (CHD). After the study follow-up, most men continued to suffer with gout attacks but also were considered high risk for coronary heart disease. And as you might know, 1 out of every 5 deaths is associated with heart disease.

Though there is little evidence to conclusively prove it, a small study presented promising information that Uric Acid levels decreased after eating a heaping helping of Bing cherries and other red or blue berries. This is a popular home remedy for lowering Uric Acid as a natural treatment of Gout.

Approval in one country does not mean approval in another, but the fact that the European Medicines Agency has approved it will carry weight when the medical authorities in other countries consider its approval.

Gout is a form of hereditary metabolic Arthritis uniquely characterized by searing pain affecting a single joint (usually a great toe, but may be a hand, elbow, or knee) accompanied by redness and warmth of the skin, swelling and inflammation.

Gout can be a life and death ailment if left untreated! I immediately made a phone call to Greg to check up! Greg followed our simple Natural Gout Cure and cured his gout, lost over 20 pounds and his blood pressure was over 15 points lower! I jokingly told him that he will be our 'cure gout poster child'.

Purine is also found in protein-rich foods such as seafood, poultry, organ meats, yeast products, as well as vegetables such as asparagus and mushrooms. Avoid these foods (and alcohol) to help prevent future flares.

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And the kicker! Men with gout were about 50% more likely to die from an acute heart attack than those men without gout! With millions of gout hospital visits each year, and over 500,000 coronary deaths per year... Can you understand the seriousness of gout?

John Mepham has lost track of the number of hours he has spent researching gout treatments. His best tip for curing gout naturally? Get to your ideal weight whatever the sacrifices may be. Learn more about natural gout treatment at www.gout-smashers-guide.com It's an e-book with an emphasis on natural gout treatment

Generally, Febuxostat has been more effective when UA levels are below 10.0 mg/dL (595 mmol/??mol). However, even if they have been above this level, it has reduced UA levels down to the target in about 40% of study patients at an 80 mg dosage, and by more at higher dosages.

You can opt for either prescribed or natural treatment for Gout or a combination of both. Remember the elevated Uric Acid level in your blood test? Uric Acid is a crystalline substance normally present in urine. It is a by-product of a substance called Purine generated by the normal break down of proteins in our cells. In Gout, Uric Acid is not metabolized properly. It forms crystals that spill into the blood stream and collect within the joint area causing severe pain and inflammation.

These are usually administered together in combination with Steroidal and non-steroidal anti-inflammatory (NSAID) treatments for Gout. A word of caution: Your physician must closely monitor ongoing Gout natural treatment. Many prescription drugs have side effects???and some are potentially fatal if combined.

Dietary regimens that help manage symptoms of Gout include a diet high in complex carbohydrates such as bread, potatoes and pasta, and low in fats and protein. Toss in some fresh fruits and veggies including cabbage, peppers and pineapple along with low-fat dairy and...voila!

The disease is more common in mature age and in the males than females. Persons exposed to the influence of lead poisoning such as plumbers, are apt to suffer from gout. Attacks of the disease are readily excited by exposure to cold, disorders of indigestion, fatigue and injuries to particular joints.

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An attack of gout may appear without warning, or there may be premonitory symptoms. Among the most common of these are disorders of the digestive organs, with a feeble and capricious appetite, flatulence, uneasiness in the right side in the region of the liver, and irritation in the urinary organs. There is also irritability, numbness and coldness in the limbs. The attack comes usually at night, usually between two and three in the morning. The affected part is found to be swollen and a deep red hue. The skin is tense and glistening and the surrounding veins are more or less distended. The attack lasts for a week or ten days during which the patient suffers from constipation, dyspepsia and extreme thirst. The urine is scanty and high coloured with a copious deposit, consisting chiefly of urates. The joint affected may become swollen but if the disease is not attended to, the swelling spreads to other joints and it becomes chronic. Joints also become enlarged and refuse to function without giving excruciating pain to the sufferer.

Unlike natural remedies for Gout, prescription drugs that treat Gout focus on different mechanisms to decrease Uric Acid levels in the blood. Medications called Uricosurics, such as Probenecid, force the secretion of Uric Acid back into the urine removing it from the blood stream, while others inhibit the initial production of Uric Acid (Allopurinol, Cholchicine) in the first place.

Your uric acid levels will have to be high. If you have gout but normal or slightly raised uric acid levels as some do, it is unlikely to be prescribed.

4.) Avoid or limit Alcohol Consumption. 5.) Exercise on a daily basis! Try to get at least 15 minutes of activity per day.

Treatment: To real treatment of gout starts with ensuring that all the orifices of the body, which expel waste and morbid matter, are activated to do their work properly. The patient should breathe fresh air, so that oxygen is available to him in larger quantities cleansing his blood of poisonous humours. The gout patient must increase his intake of water to produce more urine. He should take lukewarm water in the morning and evening mixed with the juice of mine. The pores of the skin should be activated by a cold bath every day and drying of the body with vigorous rubbing with the palms of the hand. If the pain in the joints is too severe and the patient is unable to massage his body himself, he should seek somebody else's help. Sun bathing should be undertaken to produce sweat. The head may be covered with a wet towel to save it from excessive heat of the sun. Spending half an hour in the sun will activate the sweat glands. A cold bath is recommended after a sunbath; if the patient does not feel equal to it, he would be better advised to wipe his body with a wet towel. Sun bathing should be done no more than thrice in a week. If there is no sun, sweat should be induced by a steam bath or by merely soaking one's feet in hot water.

1. Beverages such as stinging nettle and horsetail tea can help eliminate Uric Acid from the joints 2. Horseradish and parsley juices stimulate elimination of wastes 3. Birch leaf, celery and mustard seeds may also flush out uric acid 4. Herbs such as soothing Devil's Claw, and cleansing Poke Root

Noted possible side effects dizziness, drowsiness, diarrhoea, rashes, headaches, hypertension and liver function abnormalities - considered mild ones. In trials none of these side effects were reported in more than 3.5% of trial patients. The most common were liver function abnormalities.

And finally, if you want to follow the same path that Greg and hundreds of other ex-gout sufferers followed, please take a few seconds to consider:

At 120 mg it has reduced UA levels to the target of 6.0 mg/dL in over 60% of study patients. At 80 mg the numbers were around 51%. Allopurinol at a 300 mg dosage in most participants achieved this is 22% of study patients. Hence the excited buzz in rheumatology circles since these kinds of results became apparent in its trials. At or below 6.0 mg/dL gout is more likely to be cured or managed better.

You will not need to be on a low purine diet, and more good news is that it can be prescribed for the elderly. Kidney and liver disease In trials it has performed quite well with patients who have mild kidney disease. 44% of patients achieved the target at an 80 mg dosage, more at higher dosages. Better results than Allopurinol. If you have mild kidney disease (renal impairment) or mild liver problems (hepatic impairment) your doctor will judge whether Adenuric/Febuxostat can be taken safely.

It is recommended that NSAIDs or Colchicine are used along with Adenuric. This is because, as with Allopurinol, on a course of Febuxostat, there may be an initial increase in gout flares. If this happens you must battle through the attacks and continue taking Adenuric.

During the acute phase of Gout, be kind to yourself. Stay hydrated by drinking at least 96 ounces of water daily. Keep the TV remote control handy with your feet elevated; avoid weight bearing. Lose the liquor, for it only antagonizes symptoms. Follow appropriate dietary guidelines, and if you do...you can fight the complications that obesity brings to the table.

 
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Tophi If you have tophi, it's heartening to know that Febuxostat has been shown to have success against tophi. Measured tophi areas reduced in many patients with tophi. The presence of tophi will be an additional factor in favour of a decision to prescribe Febuxostat (Adenuric).

As you describe the symptoms to your doctor, he suspects (and tests for) elevated Uric Acid levels in your bloodstream. Once confirmed, your doctor will determine a suitable Gout remedy.

A powerful anti-inflammatory derivative of pineapple called Bromelain has been effective in Gout's acute treatment phase. Vitamin C may be helpful as well, but exercise caution as there are conflicting theories as to the level of therapeutic treatment of Gout.

Do you want to discover how you can cure the pain and not hide it? Are you tired of wasting over 200 dollars on a hospital visits and over-priced medication?

When in doubt about combining Gout's natural remedy as well as traditional, seek the advice of a medical professional. Below are other natural remedies for Gout to treatment that may prove beneficial for lowering Uric Acid levels and easing discomfort or maintaining urinary/fluid health:

IT'S NOT PERFECT In trials its success rate in reducing UA levels down to the important 6.0 mg/dL (357 mmol/??mol) level was not 100%. About 35% of trial patients did not achieve the target. This may have been partly because so many gout sufferers are not UA over-producers, the problem Febuxostat addresses, but under-excretors of uric acid.

Modern medicine believes gout to be hereditary since it has been found in 50 to 80 percent of the cases that the patient's parents or grand parents suffered from the disease. The disease affects the sedentary persons more than those who lead active lives, but it is not always true. On the other hand, inadequate exercise, a luxurious manner of living, habitual over-indulgence in rich foods and especially in alcohol is the precipitating factors in the onset of the disease. Some teetotalers and vegetarians are also found to be victims of gout.

For a natural dietary approach to the treatment of Gout look no further than your own kitchen! Also as Gout's natural remedy there are foods that Gouty arthritis may respond to deliciously.

Here is a list of some basic tips if you or a loved one is suffering from gout! 1.) Maintain Your Healthy Weight! 2.) Avoid Eating Meats (Purines)!

If you have severe kidney or liver problems Febuxostat is not recommended since it has not been tested in these patient groups. It is not recommended for people with heart disease or children.

No matter what Gout remedy you opt for, whether in the form of Gout's natural treatments or prescribed drugs, you vow to fight the pain of flare-ups, prevent future attacks and avoid complications such as kidney stones or immobility from chronic degeneration of joints over the span of time.

The Route to Natural Remedy for Gout Dietary supplements, vitamins and herbs are natural remedies for Gout. Included are Vitamins E and B complex, Folic Acid and evening primrose oil.

WHO WILL BE PRESCRIBED IT? The recommended dose is one 80 mg daily tablet. If after two weeks there is no reduction in UA levels, your doctor may increase the dose to 120 mg daily. Patients will need another serum UA test after two weeks treatment to find out how well it's doing. In trials it has usually worked quickly, within a couple of weeks.

This approval applies only to EU countries. Febuxostat has not yet been approved in the United States. If you are reading this from a non-EU country, or the US, you can check with your doctor to find out whether, or when, Febuxostat will be approved in your country.

However, before administering any kind of Gout remedy, first you need to know about the disorder that is ailing you.

How did he do it? He was pro-active about curing gout and began living a healthy lifestyle! And you can too! A Natural Gout Cure- No mediations needed and NO side-effects

Hippo crates in his Aphorisms speaks of gout as occurring most commonly in spring and autumn, and mentions the facts that women are less liable to it than men. Why the uric acid is found in excess is not understood by the allopathic physicians. Uric acid is formed in the system in the process of nutrition and is excreted by the kidneys. In a patient suffering from gout, the quantity of uric acid is found to be much more than normal. In a paroxysm of gout, the body appears to get rid of a lot of uric acid and there appears to be some relied but that is purely temporary.

Hot fomentation should be undertaken to reduce the pain in the joints. About 75 grammes of salt should be added to one litre of hot water for fomentation. The site of fomentation should be washed with cold water later on. Those who suffer from a constant pain should apply a paste of raw potatoes ground fine on the affected joints. The paste should be allowed to remain for some hours.

The real culprit is the type of food, which we are addicted to. Our blood is chiefly alkaline and anything that tends to produce acidity should be avoided. Treating gout in any other system is chaotic. The real cause of the disease is not attack and recourse is taken to painkillers or antidoting of the poison is under taken. The Ayurvedic practitioners prohibit the intake of fruits and vegetables on the plea that they may produce cold, which is supposed to be bad for the gout and thus deprive the patient of the real cure. Doctors have some times advised patients to have their teeth or tonsils extracted under the misconception that the seat of the disease lays there. But even the excision of these has never led to any relief to the gout patients. More on Natural Home Remedies for Gout

Causes and Symptoms: Gout is a disease of the joints and is a form of rheumatism. It is a constitutional disorder connected with excess of uric acid in the blood manifesting itself by inflammation of joints with deposition of urate of soda and also by morbid changes in various important organs.

Let me explain! Curing Gout and Decreasing Your Chance of Heart Disease My career is centered around health! Therefore, my favorite part of the newspaper is the 'Health' Section. And while reading the daily paper, I noticed an article about gout! "Gout Increases Risk of Coronary Heart Disease". I instantly flipped the page and thought 'duh'. But, after thinking about my friend Greg, his family, our friendship, his life... I immediately flipped back and read the interesting article!

Immediate pain control is priority in treating acute stages of Gout. Over the counter and prescription Analgesics such as Acetaminophen and Indomethacin, respectively, are effective in fighting pain and inflammation.

NB. The contents of this article contain medical information not medical advice. Please always discuss remedies with your doctor or other health care professional, before implementing any treatment.

Read complete and updated information on Natural Home Remedies and Herbal Treatments

Visit: http://www.natural-homeremedies.com

After a five-day period during which only fruits and vegetables are taken, milk should be added to the diet. It should preferably be boiled and taken in quantities of 250 to 500 millilitres at one time. Bread should be taken only after a fortnight of living on fruits and vegetables. Potatoes can replace bread with advantages as they contain more alkaline matter.

But like Greg (who has been gout free for almost 8 months now), you can naturally cure gout with simple gout remedies and gout prevention cures! And an added bonus, if you live a gout free lifestyle, I guarantee that you will lose weight and decrease your chance of heart disease in the process.

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Joe Barton is an expert in research and education of natural cures for gout! Joe also owns a leading natural health company which has helped thousands gain trust in natural health through a 100% guaranteed promise for all natural remedies. To discover how you could be our next gout-free customer, please click here. Natural Gout Cure

The food should consist of fresh fruits and vegetables-substances, which do not stick to the intestines. Fruits, which can be taken without peeling, should be taken. In the beginning of the treatment, the best course would be to live on fruit juices. That would give some rest to the intestines. Fruits recommended are: oranges, grape fruit, pineapple, raspberry and pear. Vegetables like the various gourds, cabbage, tomatoes and greens are the best. The more chronic the disease, the greater should be the period for which the patient should live on fruits and vegetables.

BENEFITS In large trials Febuxostat (Adenuric) has outperformed Allopurinol, the most common gout medication for long term treatment. Like Allopurinol, it works to lower uric acid production by inhibiting xanthine oxidase, an enzyme required to produce uric acid. In two major studies it reduced uric acid (UA) in more gout sufferers, and more patients reached the target 6.0 mg/dL level more quickly, than did those on Allopurinol.

A customized plan awaits your dining pleasure. And possibly, a good night's sleep!

Betty Roberts is the author of Gout-Info.com, a website dedicated to Gout sufferers.


 
 
     
 
 





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